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Test Name: | TP53 Gene Comprehensive Analysis |
Compliance: | LDT, ASR |
Test Description: | TP53, a tumor suppressor gene and transcription factor, responds to diverse cellular stresses to regulate target genes that induce apoptosis, cell cycle arrest, DNA repair, genomic stability, and senescence. More than half of all cancers contain at least one mutation in the TP53 gene. The TP53 mutations found in cancer samples are predominately missense point mutations in the DNA-binding domain that disrupt either contact with DNA or the protein's structure. |
Methodology: | PCR-Sanger sequencing analysis and Deletion/Duplication analysis of TP53 gene |
Gene Name: | TP53 |
Protein Name: | Cellular tumor antigen p53 |
Specimen Requirements: | 3-5 mL EDTA-blood |
Storage Condition: | Room Temperature |
Turn Around Time: | 14-21 working days |
OMIM: | http://www.ncbi.nlm.nih.gov/omim/?term=tp53 |
Genetic Home Reference: | http://ghr.nlm.nih.gov/gene/TP53 |
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Non-disclosure and Complaints
All data/information generated from within/related to HKMPDC and our customers are treated in strict confidence in accordance with the Personal Data (Privacy) Ordinance of Hong Kong. If you have a complaint, please contact us at the (852) 2986 1270 or email us at contact@hk-mpdc.com. All communications with HKMPDC would be dealt with in strict confidence.
Notice of Privacy Practices
This notice describes how medical information about you may be used and disclosed.
Personal health information or related information released to HKMPDC relating to the services requested may be subjected to re-disclosure by HKMPDC to health care providers, such as doctors, nurses, and others involved in the delivery of the services.
We may also disclose medical information about you to authorised public health or government officials for public health activities as required by law.
Copyright © 2013 香港分子病理檢驗中心 Hong Kong Molecular Pathology Diagnostic Centre Limited (HKMPDC). All Rights Reserved.
Information Updated 29 June, 2020.
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