HKPMDC
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Hereditary Cancer
Test Name: TP53 Gene Comprehensive Analysis
Compliance:LDT, ASR
Test Description:TP53, a tumor suppressor gene and transcription factor, responds to diverse cellular stresses to regulate target genes that induce apoptosis, cell cycle arrest, DNA repair, genomic stability, and senescence. More than half of all cancers contain at least one mutation in the TP53 gene. The TP53 mutations found in cancer samples are predominately missense point mutations in the DNA-binding domain that disrupt either contact with DNA or the protein's structure.
Methodology:PCR-Sanger sequencing analysis and Deletion/Duplication analysis of TP53 gene
Gene Name:TP53
Protein Name:Cellular tumor antigen p53
Specimen Requirements:3-5 mL EDTA-blood
Storage Condition:Room Temperature
Turn Around Time:14-21 working days
OMIM:http://www.ncbi.nlm.nih.gov/omim/?term=tp53
Genetic Home Reference:http://ghr.nlm.nih.gov/gene/TP53
Phone:+852.2986.1270
Fax:+852.2527.7028
E-mail:contact@hk-mpdc.com
27/F., Strand 50, No.50 Bonham Strand, Sheung Wan, Hong Kong
Opening Hours
Mondays to Fridays: 09:00-18:00
Saturdays: 09:00-16:00
Sundays and Public Holidays: Closed

For specimen pickup arrangements, please phone +852.2986.1270




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