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Test Name: Microsatellite Instability Test
Test Description:This Microsatellite Instability (MSI) test evaluates changes in microsatellite length of tumor tissue compared to normal tissue. MSI High (MSI-H) indicates that 2 or more microsatellites show instability. The presence of MSI-H indicates a deficient DNA mismatch repair process in the tumor tissue. MSI-H colonic and gastric tumors are associated with favorable prognosis. There is also evidence to suggest that colorectal cancer patients with MSI-H tumors respond differently to fluorouracil-based chemotherapy. This test is used to screen patients suspected to have an inherited cancer syndromes involving the DNA mismatch repair (MMR) process, such as Hereditary Non-Polyposis Colorectal Cancer (HNPCC / Lynch Syndrome) or confirm a clinical diagnosis.
Methodology:Multiplex PCR and capillary gel electrophoresis
Gene Name:
Protein Name:
Specimen Requirements:FFPE Slides: 5-10 4µm FFPE tissue sections stained with H&E. One section must be mounted with tumor region (region of interest) marked. Please include a copy of corresponding surgical pathology report. FFPE Block: Paraffin-embedded, formalin-fixed tissue block containing adequate amounts of tumor to be analyzed with areas of tumor marked. Please include a copy of corresponding surgical pathology report.
Storage Condition:Room Temperature
Turn Around Time:3-5 working days from day of specimen received
Genetic Home Reference:
27/F., Strand 50, No.50 Bonham Strand, Sheung Wan, Hong Kong
Opening Hours
Mondays to Fridays: 09:00-18:00
Saturdays: 09:00-16:00
Sundays and Public Holidays: Closed

For specimen pickup arrangements, please phone +852.2986.1270

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